| 发明名称 |
NOVEL COMPOSITIONS AND METHODS |
| 摘要 |
The present invention is directed to a polypeptide which comprises: (i) an Rv2386c protein sequence; (ii) a variant of an Rv2386c protein sequence; or (iii) an immunogenic fragment of an Rv2386c protein sequence. In other aspects the invention is directed to associated polynucleotides, fusion proteins and methods for the treatment or prevention of tuberculosis. |
| 申请公布号 |
US2014178423(A1) |
申请公布日期 |
2014.06.26 |
| 申请号 |
US201313930587 |
申请日期 |
2013.06.28 |
| 申请人 |
GlaxoSmithKline Biologicals S.A. |
发明人 |
Mettens Pascal;Brown James;Murphy Dennis |
| 分类号 |
A61K39/04 |
主分类号 |
A61K39/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the treatment or prevention of latent tuberculosis comprising the administration of a polypeptide
comprising:
(i) an Rv3616c protein sequence;(ii) a variant of an Rv3616c protein sequence; or(iii) an immunogenic fragment of an Rv3616c protein sequence; to a subject in need thereof, wherein said polypeptide induces an immune response. |
| 地址 |
Rixensart BE |
