ISOXAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME

摘要

The present invention provides isoxazole derivatives represented by the following formula (I): (wherein R<1> represents a hydrogen atom, C1 - C20 hydrocarbon group or ? C(=O)OR<1a> (wherein R<1a> represents a C1 - C10 alkyl group, etc.); R<2> and R<3> represent a hydrogen atom, halogen atom, hydroxy group, C1 - C20 alkyl group or C6 - C20 aryl group, etc.; R<4> represents a hydrogen atom, halogen atom, hydroxy group, cyano group, nitro group, amino group, C1 - C20 hydrocarbon group, C1 - C10 alkoxy group, C1 - C10 acyl group, 5- to 7-membered heterocyclic group, etc.; R<5> represents a hydrogen atom, halogen atom, hydroxy group, optionally substituted C1 - C20 hydrocarbon group, C1 - C20 alkoxy group, 5- to 7-membered heterocyclic group, etc.; and, n represents 0, 1, 2, 3 or 4), and a process of producing the same. The compounds are useful as intermediates for synthesis of pharmaceutical compounds, agricultural chemicals, dye compounds, etc. having the isoxazole skeleton.