| 摘要 |
The present invention relates to a pharmaceutical composition comprising a sulfamide derivative having an adamantyl group as an active ingredient for preventing or treating brain diseases or ischemic heart diseases. The sulfamide derivative compound having an adamantyl group according to the present invention may efficiently inhibit the activity of 11β-HSD1, and therefore, can be effectively used in preventing or treating not only ischemic heart diseases but also various 11β-HSD1-mediated brain diseases such as neurodegenerative diseases, cerebrovascular diseases caused by ischemia or reperfusion and mental diseases. |
