| 发明名称 |
2,3-DIHYDROIMIDAZO[1,2-C]PYRIMIDIN-5(1H)-ONE COMPOUNDS USE AS LP-PLA² INHIBITORS |
| 摘要 |
<p>Disclosed are 2,3-dihydroimiazo[1,2-c]pyrimidin-5(IH)-one compounds that inhibit Lp-PLA2,processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.</p> |
| 申请公布号 |
EP2739627(A1) |
申请公布日期 |
2014.06.11 |
| 申请号 |
EP20120818124 |
申请日期 |
2012.07.25 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
WAN, ZEHONG;LONG, KAI;SANG, YINGXIA;SU, XIAOBO |
| 分类号 |
C07D487/04;A61K31/519;A61P9/10;A61P25/28 |
主分类号 |
C07D487/04 |
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