发明名称 |
OXAZOLIDINONE CONTAINING DIMER COMPOUNDS, COMPOSITIONS AND METHODS TO MAKE AND USE. |
摘要 |
Dosage forms or pharmaceutical compositions comprise a compound having the structure of Formula IV: wherein n is a non-negative integer; wherein each Z is an oxazolidinone-containing moiety having antibiotic activity in vivo upon cleaving, wherein M is independently OR1 or NR1R2; wherein R1 and R2 are independently selected from the group consisting of H, an optionally-substituted hydrocarbyl residue or a pharmaceutically acceptable cation; wherein the compound in the dosage form or a pharmaceutical composition is present in an amount effective for treating or preventing an antibacterial infection in a mammalian subject. Methods of preparing and using these dosage forms or pharmaceutical compositions are also disclosed. |
申请公布号 |
MX2014001282(A) |
申请公布日期 |
2014.06.10 |
申请号 |
MX20140001282 |
申请日期 |
2014.01.30 |
申请人 |
TRIUS THERAPEUTICS, INC. |
发明人 |
FINN, JOHN;HESTER, D., KEITH;DUGUID, ROBERT, J. |
分类号 |
A61K31/675;A61P31/04;C07D413/14 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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