发明名称 |
METHODS OF IDENTIFYING SURROGATE IMAGING AGENTS FOR ALPHA EMITTER RADIOPHARMACEUTICALS AND THEIR USE IN TREATMENT OF DISEASE |
摘要 |
In accordance with one or more embodiments, the present invention provides a series of identified radiopharmaceuticals herein termed "imaging surrogates" whose pharmacokinetic behavior matches that of the alphaRPT for several alphaRPTs currently under investigation as cancer therapeutics. Methods for identifying imaging surrogates are also provided. These imaging surrogates can be used to implement a treatment planning approach to radiopharmaceutical therapy of alpha-emitters, enabling treatment to the maximum tolerated organ absorbed dose for individual patients. |
申请公布号 |
WO2014085530(A1) |
申请公布日期 |
2014.06.05 |
申请号 |
WO2013US72147 |
申请日期 |
2013.11.27 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
SGOUROS, GEORGE;HOBBS, ROBERT;SONG, HONG |
分类号 |
A61K51/04;A61K49/00;A61K49/06;A61K51/00 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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