| 摘要 |
PROBLEM TO BE SOLVED: To provide a skin external preparation having a new emulsifier type capable of being suitably applied to a cosmetic, a pharmaceutical composition and the like, and a production method of the skin external preparation.SOLUTION: An O/W/O emulsifier-type skin external preparation contains an amphipathic molecule, water and oil, where the aqueous phase of the skin external preparation comprises an aqueous phase having a vesicle and an oil-in-water phase having a lamellar liquid crystal emulsion. A production method of the skin external preparation comprises the steps of: dispersing an aqueous phase previously prepared from the vesicle and the lamellar liquid crystal emulsion to obtain a dispersion liquid; and dispersing the obtained dispersion liquid in an oil phase to obtain a skin external preparation. |
