发明名称 |
High Fidelity Restriction Endonucleases |
摘要 |
Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer. |
申请公布号 |
US2014154780(A1) |
申请公布日期 |
2014.06.05 |
申请号 |
US201314137660 |
申请日期 |
2013.12.20 |
申请人 |
New England Biolabs, Inc. |
发明人 |
Zhu Zhenyu;Quimby Aine;Guan Shengxi;Sun Dapeng;Huang Yishu;Lai Xuhui;Chan Siu-hong;Li Xianghui;Xu Shuang-Yong;Zhang Chunhua |
分类号 |
C12N9/22;C12Q1/68 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Ipswich MA US |