发明名称 |
ACADESINE DERIVATIVES, PRODUCTS AND COMPOSITIONS INCLUDING SAME,THERAPEUTIC USES THEREOF AND METHODS FOR SYNTHESIZING SAME |
摘要 |
Acadesine derivatives as a drug, as well as the derivatives for the treatment of cancer and in particular for the treatment of chronic myeloid leukemia are described. Also, product containing the derivatives and at least one second active ingredient as a combination product for simultaneous, separate or sequential administration, in the treatment of cancer, as well as a pharmaceutical composition containing the derivatives and a pharmaceutically acceptable carrier are described. Finally, a method for inhibiting the in vitro cell proliferation including the placement of an in vitro cell in contact with the derivatives and methods for synthesis of said derivatives and methods for synthesis of the derivatives are described. |
申请公布号 |
ZA201307451(B) |
申请公布日期 |
2014.05.28 |
申请号 |
ZA20130007451 |
申请日期 |
2013.10.07 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM (EPST));UNIVERSITE NICE SOPHIA ANTIPOLIS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) |
发明人 |
BENHIDA RACHID;AUBERGER PATRICK;DRIOWYA MOHSINE;PUISSANT ALEXANDRE;ROBERT GUILLAUME;MALNUIT VINCENT |
分类号 |
A61K;A61P;C07D;C07H |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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