发明名称 |
Pyrrolopyrimidine compounds for the treatment of cancer |
摘要 |
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemia (ALL) cells and a potential cause of ALL chemoresistance. Hence, we investigated whether the development of small molecule Mer inhibitors was possible. A first aspect of the present invention is a compound (sometimes referred to as an "active compound" herein) of Formula I, IA, or IB. |
申请公布号 |
AU2012318896(A1) |
申请公布日期 |
2014.05.22 |
申请号 |
AU20120318896 |
申请日期 |
2012.10.01 |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
WANG, XIAODONG;LIU, JING;ZHANG, WEIHE;FRYE, STEPHEN;KIREEV, DMITRI |
分类号 |
C07D471/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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