发明名称 |
METHODS FOR PRODUCING LIPOSOMES |
摘要 |
The invention discloses a method for the formation of liposomes by using high shear mixing of aqueous solution of lipid powder; the lipid powder can be produced by any known technique. Components of the liposomes include but are not limited to cationic lipids, immunostimulatory/immunopotentiators and macromolecules as components for the liposome formation. The disclosed method describes the formulation of stable liposomes solitary or complexing high concentrations of macromolecules such as proteins, DNA and RNA having opposite charge of the liposomes by high shear mixing where aggregation is avoided due to the formulation method. |
申请公布号 |
EP2729127(A2) |
申请公布日期 |
2014.05.14 |
申请号 |
EP20120746008 |
申请日期 |
2012.07.03 |
申请人 |
STATENS SERUM INSTITUT |
发明人 |
ANDREASEN, LARS, VIBE;WOOD, GRITH, KRØYER;CHRISTENSEN, DENNIS |
分类号 |
A61K9/127 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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