COMPOSITION FOR PREVENTING OR TREATING BRODY DISEASE AND BRODY SYNDROME COMPRISING MG53 INHIBITOR

摘要

The present invention relates to a composition for the prevention or treatment of brody disease and brody syndrome comprising a mitsugumin 53 (MG53) inhibitor, and a disease treatment method using the composition for the prevention or treatment of brody disease and brody syndrome comprising a MG53 inhibitor. In addition, the present invention relates to a method for screening a therapeutic agent for muscle diseases by determining a medicine which inhibits interaction between MG53 and sarcoplasmic reticulum Ca2+-ATPase 1a (SERCA1a) as the therapeutic agent for muscle diseases including brody disease and brody syndrome.