摘要 |
A bsochip for multiplex genetic identification is disclosed. An bsochip for separating and detecting a plurality of DNA fragments includes a set of inputs and chambers for receiving a sample matrix of genetic material and reagents needed to conduct a polymerase chain reaction amplification of the genetic material. The bioehip also includes a plurality of separation and detection chambers that physically separate different DNA fragments that have been marked with labels that emit similar colors. A method of detecting nucleic acid fragments is also provided. Each chamber has at least one set of probes disposed therein, each set of probes being capable of binding to a different target nucleic acid sequence relative to the other sets of probes. The method includes providing a sample comprising a plurality of sets of nucleic acid fragments, placing at least a portion of the sample into each of the plurality of chambers. |