发明名称 METHOD FOR PREDICTING THE RESPONSE TO TREATMENT WITH AN HER2-BLOCKING AGENT
摘要 The invention relates in particular to an in vitro or ex vivo method for predicting the response of a patient to treatment with at least one HER2-blocking agent, said method including the steps of: i) identifying the nucleotide at the rs3746083 polymorphic site, for at least one allele, in particular the two alleles of the gene coding the tristetraprolin protein, in a biological sample from said patient; and/or ii) determining the concentration of the tristetraprolin protein in a biological sample from said patient, wherein said patient is suffering from HER2-positive cancer.
申请公布号 EP2718462(A1) 申请公布日期 2014.04.16
申请号 EP20120730411 申请日期 2012.06.07
申请人 UNIVERSITE DE NICE SOPHIA ANTIPOLIS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 发明人 PAGES, GILLES
分类号 C12Q1/68;C12N15/11;G01N33/574 主分类号 C12Q1/68
代理机构 代理人
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