发明名称 |
FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB (CD137) |
摘要 |
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject. |
申请公布号 |
SI1670828(T1) |
申请公布日期 |
2014.03.31 |
申请号 |
SI20040032112T |
申请日期 |
2004.10.12 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
JURE-KUNKEL MARIA;HEFTA LAURA J.;SANTORO MARC;GANGULY SUBINAY;HALK EDWARD L. |
分类号 |
A61K39/00;C07K16/28 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|