| 摘要 |
Vinylcephems. [I; R2 = carboxy or protected carboxy; R6 = amino or protected amino; A = CNOR4; R4=H, lower alkyl, or carboxy-substituted lower alkyl were prepd. by the reaction of II [X1 = halogen with NH2CSR6. Thus, 1.2 g benzhydryl 7-(4-bromo2-methoxyiminoacetamido)-3- vinyl-3-cephem-4-carboxylate was reacted with 0.5 g thiourea, 0.7 g sodiumacetate and 20 ml tetrahydrofuran to give 1.05 g benzhydryl 7- [2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido -3-vinyl-3-cephem-4- carboxylate.
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