发明名称 |
Method for producing cyclic sulfonic acid ester and intermediate thereof |
摘要 |
The present invention is directed to provide an efficient production method which is capable of not only obtaining a cyclic sulfonic acid ester (sultone) at low cost and in high yield, but also the sulfonic acid ester (sultone) stably even in a commercial scale. The present invention relates to a method for producing hydroxysultone comprising a first step where a diol having a specified structure and a thionyl halide are reacted to obtain a cyclic sulfite having a specified structure, and a second step where the cyclic sulfite is reacted with water or/and alcohol; a method for producing an unsaturated sultone having a specified structure comprising a third step where a hydroxylsultone having a specified structure is reacted with an acid halide or an acid anhydride to obtain an intermediate, subsequently the intermediate is treated with a base; as well as a cyclic sulfite having a specified structure. |
申请公布号 |
US8673963(B2) |
申请公布日期 |
2014.03.18 |
申请号 |
US201013388405 |
申请日期 |
2010.08.03 |
申请人 |
KURAMOTO AYAKO;OKAMOTO KUNIAKI;WATAHIKI TSUTOMU;SUMINO MOTOSHIGE;WAKO PURE CHEMICAL INDUSTRIES, LTD. |
发明人 |
KURAMOTO AYAKO;OKAMOTO KUNIAKI;WATAHIKI TSUTOMU;SUMINO MOTOSHIGE |
分类号 |
A61K31/381;C07D327/10 |
主分类号 |
A61K31/381 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|