发明名称 Method for producing cyclic sulfonic acid ester and intermediate thereof
摘要 The present invention is directed to provide an efficient production method which is capable of not only obtaining a cyclic sulfonic acid ester (sultone) at low cost and in high yield, but also the sulfonic acid ester (sultone) stably even in a commercial scale. The present invention relates to a method for producing hydroxysultone comprising a first step where a diol having a specified structure and a thionyl halide are reacted to obtain a cyclic sulfite having a specified structure, and a second step where the cyclic sulfite is reacted with water or/and alcohol; a method for producing an unsaturated sultone having a specified structure comprising a third step where a hydroxylsultone having a specified structure is reacted with an acid halide or an acid anhydride to obtain an intermediate, subsequently the intermediate is treated with a base; as well as a cyclic sulfite having a specified structure.
申请公布号 US8673963(B2) 申请公布日期 2014.03.18
申请号 US201013388405 申请日期 2010.08.03
申请人 KURAMOTO AYAKO;OKAMOTO KUNIAKI;WATAHIKI TSUTOMU;SUMINO MOTOSHIGE;WAKO PURE CHEMICAL INDUSTRIES, LTD. 发明人 KURAMOTO AYAKO;OKAMOTO KUNIAKI;WATAHIKI TSUTOMU;SUMINO MOTOSHIGE
分类号 A61K31/381;C07D327/10 主分类号 A61K31/381
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