发明名称 |
TARGET PEPTIDES FOR COLORECTAL CANCER THERAPY AND DIAGNOSTICS |
摘要 |
<p>A set of target peptides are presented by HLA A*0201, B*0301, B*0702 and B*2705 on the surface of disease cells. They are envisioned to, among other things, stimulate an immune response to the proliferative disease, e.g., colorectal cancer, to function as immunotherapeutics in adoptive T cell therapy or as a vaccine, facilitate antibody recognition of tumor boundaries in surgical pathology samples, act as biomarkers for early detection and/or diagnosis of the disease, and/or act as targets in the generation antibody-like molecules which recognize the target-peptide/MHC complex.</p> |
申请公布号 |
CA2883673(A1) |
申请公布日期 |
2014.03.13 |
申请号 |
CA20132883673 |
申请日期 |
2013.09.05 |
申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION;THE UNIVERSITY OF BIRMINGHAM |
发明人 |
HUNT, DONALD F.;SHABANOWITZ, JEFFREY;ABELIN, JENNIFER G.;COBBOLD, MARK;PENNY, SARAH AMY |
分类号 |
C07K16/18;A61K35/17;A61K39/00;A61P35/00;A61P37/04;C07K14/47;C12N5/0783;C12N5/0784 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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