RAPID FORMATION OF CHITOSAN SPONGES USING GUANOSINE 5' -DIPHOSPHATE: INJECTABLE SCAFFOLDS FOR TISSUE REGENERATION AND DRUG DELIVERY

摘要

It is disclosed Guanosine 5'-Diphosphate (GDP) crosslinked chitosan sponge or gelling composition which is used as a scaffold for tissue regeneration applications such as neural, cardiac, cartilage and bone regeneration. In addition, the sponge acts as a drug delivery system to provide local controlled drug release, such as delivering anti-cancer drugs locally at the tumor site.