THIOXOQUINAZOLINONE DERIVATIVES AS GLUTAMINYL CYCLASE INHIBITORS

摘要

Compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof wherein: R¹ represents and R², R³, R⁴, R⁵, R⁶, X₁, X₂, X₃, X₄, Y and Z are as defined throughout the description and the claims.