| 发明名称 |
ANDROGEN RECEPTOR MODULATING CARBOXAMIDES |
| 摘要 |
<p>Compounds of formula (I) or (II) wherein Rx, Rz, R9, R10, R14, R14′, R15, R15′, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.</p> |
| 申请公布号 |
EP2699561(A1) |
申请公布日期 |
2014.02.26 |
| 申请号 |
EP20120722174 |
申请日期 |
2012.04.20 |
| 申请人 |
ORION CORPORATION |
发明人 |
TOERMAEKANGAS, OLLI;WOHLFAHRT, GERD;SALO, HARRI;RAMASUBRAMANIAN, RATHNA, DURGA;PATRA, PRANAB, KUMAR;MARTIN, ARPUTHARAJ, EBENEZER;HEIKKINEN, TERHI;VESALAINEN, ANNIINA;MOILANEN, ANU;KARJALAINEN, ARJA |
| 分类号 |
C07D401/04;A61K31/4164;A61P35/00;C07D403/04;C07D403/12;C07D413/12;C07D413/14;C07D471/04;C07D487/04;C07D513/04 |
主分类号 |
C07D401/04 |
| 代理机构 |
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