发明名称 |
Means and methods for assessing increased peroxisomal proliferation |
摘要 |
The present invention pertains to the field of toxicological assessments of risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal proliferation. It also relates to a method of determining whether a compound is capable of inducing such peroxisomal proliferation in a subject and to a method of identifying a drug for treating increased peroxisomal proliferation. Furthermore, the present invention relates to a data collection of characteristic values of at least five metabolites, a data storage medium for the data collection, and a system and a device for diagnosing increased peroxisomal proliferation. Finally, the present invention pertains to the use of a group of metabolites or means for the determination thereof for the manufacture of a diagnostic device or composition for diagnosing increased peroxisomal proliferation in a subject. |
申请公布号 |
US8658427(B2) |
申请公布日期 |
2014.02.25 |
申请号 |
US20090994705 |
申请日期 |
2009.05.26 |
申请人 |
VAN RAVENZWAAY BENNARD;MELLERT WERNER;FABIAN ERIC;STRAUSS VOLKER;WALK TILMANN B.;LOOSER RALF;LEIBOLD EDGAR;KAMP HENNICKE;CUNHA GEORGIA COELHO PALERMO;HEROLD MICHAEL MANFRED;WIEMER JAN C;PROKOUDINE ALEXANDRE;BASF SE |
发明人 |
VAN RAVENZWAAY BENNARD;MELLERT WERNER;FABIAN ERIC;STRAUSS VOLKER;WALK TILMANN B.;LOOSER RALF;LEIBOLD EDGAR;KAMP HENNICKE;CUNHA GEORGIA COELHO PALERMO;HEROLD MICHAEL MANFRED;WIEMER JAN C;PROKOUDINE ALEXANDRE |
分类号 |
G01N33/92;G01N33/68 |
主分类号 |
G01N33/92 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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