发明名称 |
Bis-quaternary ammonium cyclophane compounds that interact with neuronal nicotinic acetylcholine receptors |
摘要 |
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders. |
申请公布号 |
US8653275(B2) |
申请公布日期 |
2014.02.18 |
申请号 |
US20070300197 |
申请日期 |
2007.05.11 |
申请人 |
CROOKS PETER;DWOSKIN LINDA P.;ZHENG GUANGRONG;SUMITHRAN SANGEETHA;ALLEN DAVIS D.;ZHENG ZHENFA;LOCKMAN PAUL;UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
CROOKS PETER;DWOSKIN LINDA P.;ZHENG GUANGRONG;SUMITHRAN SANGEETHA;ALLEN DAVIS D.;ZHENG ZHENFA;LOCKMAN PAUL |
分类号 |
C07D211/68;A61K31/435 |
主分类号 |
C07D211/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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