发明名称 |
PHARMACEUTICAL COMPOSITION WITH CONTROLLED ACTIVE INGREDIENT DELIVERY FOR ACTIVE INGREDIENTS WITH GOOD SOLUBILITY IN WATER |
摘要 |
<p>A pharmaceutical preparation comprising: a) a core with an active ingredient and with an organic acid and/or the salt of an organic acid; and b) a coating which envelops the core and which comprises a polymer content of (meth)acrylate copolymers which have not more than 15% by weight of cationic or anionic groups, and which comprises at least 60% by weight of a (meth)acrylate copolymer which is composed of free-radically polymerized units of 93 to 98% by weight C1- to C4-alkyl esters of acrylic or of methacrylic acid and 7 to 2% by weight (meth)acrylate monomers having a quaternary ammonium group in the alkyl radical, wherein the active ingredient has a solubility in water of at least 10 g/l at 20° C. and the coating comprises silicon dioxide particles having an average particle size in the range from 1 to 50 mum.</p> |
申请公布号 |
KR20140019038(A) |
申请公布日期 |
2014.02.13 |
申请号 |
KR20147002284 |
申请日期 |
2006.09.21 |
申请人 |
EVONIK ROEHM GMBH |
发明人 |
PETEREIT HANS ULRICH;RAVISHANKAR HEMA;BODINGE SHRADDHA |
分类号 |
A61K9/28;A61K9/20;A61K47/34 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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