发明名称 |
MODULATORS OF PLEXIN B2 ACTIVITY |
摘要 |
<p>Disclosed herein are novel compositions and methods for the inhibition of Plexin B2-mediated Angiogenin activity. Such compositions and methods are useful, for example, for the treatment of cancer, the treatment of wet AMD and the inhibition of angiogenesis. Also disclosed herein are methods of determining whether a test agent is a modulator of Plexin B2 activity.</p> |
申请公布号 |
EP2691420(A1) |
申请公布日期 |
2014.02.05 |
申请号 |
EP20120764572 |
申请日期 |
2012.03.28 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;TUFTS MEDICAL CENTER, INC. |
发明人 |
HU, GUOFU;YU, WENHAO |
分类号 |
C07K16/30;A61K39/395;A61P35/00;C07K16/28;C12N15/113;C12P21/08 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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