摘要 |
FIELD: chemistry.SUBSTANCE: in formula III:,each of Xand Xis independently selected from a bond, -CH-, -O- or -S- and at least one of Xand Xis selected from -CH-, -O- or -S-; each of Rand Ris independently selected from hydrogen or Caryl, optionally substituted with one or more Rand at least one of Rand Ris selected from Caryl, optionally substituted with one or more R; each of Zand Zis selected from -N(R)-, each of W, W, W, W, W, W, Wand Wis independently selected from N or C(R), where Rin each case is selected from hydrogen; each of R, R, R, R, R, R, Rand Rin each case is independently selected from hydrogen or R; each of m and n is 0; Rin each case is independently selected from halogen, hydroxy group, amino group, -Land -L-R; Lin each case is selected from C-C-alkyl; values of radicals T, R, R, Rare given in the claim. The invention also relates to a pharmaceutical composition containing said compounds, a method of inhibiting HCV replication, a method of treating HCV infection and a method of producing said compounds.EFFECT: high efficiency of using compounds.7 cl, 6 tbl, 28 ex |