发明名称 ANTIVIRAL COMPOUNDS
摘要 FIELD: chemistry.SUBSTANCE: in formula III:,each of Xand Xis independently selected from a bond, -CH-, -O- or -S- and at least one of Xand Xis selected from -CH-, -O- or -S-; each of Rand Ris independently selected from hydrogen or Caryl, optionally substituted with one or more Rand at least one of Rand Ris selected from Caryl, optionally substituted with one or more R; each of Zand Zis selected from -N(R)-, each of W, W, W, W, W, W, Wand Wis independently selected from N or C(R), where Rin each case is selected from hydrogen; each of R, R, R, R, R, R, Rand Rin each case is independently selected from hydrogen or R; each of m and n is 0; Rin each case is independently selected from halogen, hydroxy group, amino group, -Land -L-R; Lin each case is selected from C-C-alkyl; values of radicals T, R, R, Rare given in the claim. The invention also relates to a pharmaceutical composition containing said compounds, a method of inhibiting HCV replication, a method of treating HCV infection and a method of producing said compounds.EFFECT: high efficiency of using compounds.7 cl, 6 tbl, 28 ex
申请公布号 RU2505539(C2) 申请公布日期 2014.01.27
申请号 RU20110130831 申请日期 2009.12.22
申请人 EHBBOTT LEHBORETRIZ 发明人 DEGOJ DEHVID A.;DONNER PAMELA L.;KATI UORREN M.;KHATCHINS CHARL'Z V.;KRJUGER ALLAN K.;RANDOLF DZHON T.;MOTTER KRISTOFER EH.;KRISHNAN PREETKHI;MISTRI NEETA K.;PAJLOT-MATIAS TAMI DZH.;PATEL SACHIN V.;LI SJAOJAN';SOLTVEDEL TODD N.;NEL'SON LISSA T.
分类号 C07D471/04;A61K31/4375;A61K31/519;A61P31/14 主分类号 C07D471/04
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