R4 do-25fl /2013 The present invention relates to the provision of novel immunogens comprising an antigenic PCSK9 peptide linked to an immunogenic carrier for the prevention, treatment or alleviation of PCSK9-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
申请公布号
AU2013273674(A1)
申请公布日期
2014.01.16
申请号
AU20130273674
申请日期
2013.12.18
申请人
PFIZER VACCINES LLC
发明人
CHAMPION, BRIAN ROBERT;CONTILLO JR., LEONARD GABRIEL;EISENBRAUN, MICHAEL DALE;FRASER, JAMES DOWNEY;HAWKINS, JULIE JIA LI;MERSON, JAMES RICHARD;PIERCE, BRIAN GREGORY;QIU, XIAYANG;ULLAH, JAKIR HUSSAIN;WYATT, DAVID MICHAEL