| 发明名称 |
INHIBITION OF CYP3A DRUG METABOLISM |
| 摘要 |
The present invention provides methods, pharmaceutical compositions, medicaments, and pharmaceutical kits that employ the use of boceprevir as a CYP3A4/5 inhibitor to improve the pharmacokinetics of therapeutic compounds metabolized by cytochrome P450 3A4/5 (CYP3A4/5) enzymes. |
| 申请公布号 |
EP2598159(A4) |
申请公布日期 |
2014.01.08 |
| 申请号 |
EP20110812998 |
申请日期 |
2011.07.25 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
GHOSAL, ANIMA.;GUPTA, SAMIR.;KISHNANI, NARENDRA.;KASSERRA, CLAUDIA.;O`MARA, EDWARD. |
| 分类号 |
A61K38/21;A01N37/18;A61K38/07 |
主分类号 |
A61K38/21 |
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