发明名称 |
MicroRNAS FOR THE GENERATION OF ASTROCYTES |
摘要 |
A method of generating a population of cells useful for treating a nerve disease or disorder in a subject, the method comprising up-regulating a level of at least one exogenous miRNA in mesenchymal stem cells (MSCs) and/or down-regulating a level of at least one miRNA using a polynucleotide agent that hybridizes to the miRNA, thereby generating the population of cells useful for treating the nerve disease or disorder. Isolated populations of cells with an astrocytic phenotype generated thereby and uses thereof are also provided. |
申请公布号 |
WO2013124817(A3) |
申请公布日期 |
2014.01.03 |
申请号 |
WO2013IB51430 |
申请日期 |
2013.02.21 |
申请人 |
BRAINSTEM BIOTEC LTD.;HENRY FORD HEALTH SYSTEM |
发明人 |
BRODIE, CHAYA;SLAVIN, SHIMON |
分类号 |
C12N5/079;A61P25/00;A61P25/16;C12N15/113 |
主分类号 |
C12N5/079 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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