| 摘要 |
Compound corresponding to general formula (I)in which Rrepresents a hydrogen; n represents an integer 1 or 2 and m represents an integer 2; A is a covalent bond or a C-alkylene group; Rrepresents a group Rwhich is optionally substituted by one or more groups Rand/or R; Rrepresents a group selected from a pyridinyl and quinolinyl; Rrepresents a halogen atom, a cyano, -CHCN, nitro, hydroxyl, Calkyl, Calkoxy, Chaloalkyl, Chaloalkoxy, Ccycloalkyl, Ccycloalkyl-Calkylene or Ccycloalkyl-Calkylene-O- group, or a group NRR, NRCOR, NRCOR, NRSOR, CONRR, SORor SONRR; Rrepresents a group selected from a thienyl, isoxazolyl, pyrazolyl, phenyl, pyridinyl, pyridazinyl, pyrimidinyl, naphthalenyl, quinolinyl, isoquinolinyl, wherein the group or groups Rbeing able to be substituted by one or more groups Rwhich are identical or different from one another; Rrepresents a hydrogen or fluorine atom, a Calkyl group or a trifluoromethyl group; Rrepresents a thiazole which is optionally substituted by one or more substituents selected from a halogen atom, a Calkyl, Chaloalkyl, CONRRor pyridinyl; in the form of a base or of an addition salt with an acid. Therapeutic use. |
