发明名称 |
MARKER FOR DIAGNOSING EFFECT OF ANTICANCER AGENT |
摘要 |
<p>The present invention enables to realize a convenient determination of a therapeutic effect of an anticancer agent on a cancer. Specifically, the present invention provides a diagnostic marker for an effect of an anticancer agent on a cancer, comprising a substance having an affinity for a fragment of an extracellular domain of c-MET; a diagnostic reagent for an effect of an anticancer agent on a cancer, comprising a substance having an affinity for a fragment of an extracellular domain of c-MET and the fragment of the extracellular domain of c-MET; and a method of testing an effect of an anticancer agent on a cancer, comprising (a) measuring a concentration of a fragment of an extracellular domain of c-MET in a biological sample from a subject, and (b) comparing the measured concentration of the fragment of the extracellular domain of c-MET with an indicator which presents a relationship between a concentration of the fragment of the extracellular domain of c-MET and the effect of the anticancer agent on the cancer.</p> |
申请公布号 |
EP2554993(A4) |
申请公布日期 |
2013.12.25 |
申请号 |
EP20110765360 |
申请日期 |
2011.03.18 |
申请人 |
FUJIREBIO INC. |
发明人 |
ISE, NOBUYUKI;NAMBARA, DAISUKE;OMI, KAZUYA |
分类号 |
G01N33/50;C07K16/28;G01N33/574 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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