发明名称 METHOD AND APPARATUS FOR PROLIFERATION AND ACTIVATION OF FIBROBLAST
摘要 PROBLEM TO BE SOLVED: To provide an electric treatment method and an electric apparatus which are based on discovery by experiments and clinical trials, have extremely high safety and can easily proliferate and activate a fibroblast since a fibroblast existing in dermis or the like under the skin is a basic cell that can secrete an extracellular matrix in a supporting tissue (a connective tissue) in the body, a conventional method for proliferating/activating a fibroblast artificially comprises applying a relatively high voltage/electrical field and this method may cause the deterioration in safety or the damage to the skin.SOLUTION: As a result of repeated experiments and clinical trials, it is found that a fibroblast can be physiologically activated and can self-propagate by applying a far lower electric field than those employed in conventional methods. Consequently, it is confirmed that electrical field intensity of 0.001 to 0.3 V/cm is a proper electrical field region to be applied to a subepidermal region. On the basis of this confirmation, a method and an apparatus both for proliferating/activating a fibroblast by applying such an electrical field are invented. The electrical apparatus is so adapted that a battery composed of a metal and a semiconductor material having different electrical affinities from each other is used as a skin attachment tool.
申请公布号 JP2013252117(A) 申请公布日期 2013.12.19
申请号 JP20120130996 申请日期 2012.06.08
申请人 POLYTRONICS LTD 发明人 KASANO HIROYUKI
分类号 C12N5/077;C12M3/00 主分类号 C12N5/077
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