METHOD FOR MAKING SELF-ASSEMBLING, COLLAGEN-BASED MATERIAL FOR CORNEAL REPLACEMENT

摘要

A material derived from sea cucumber collagen fibrils is suitable for use in corneal replacements or as an implantable contact lens. To produce material, the collagen fibrils are centrifuged into orthogonal stacks of lamellae comprised of aligned fibrils. The resulting structure is a transparent film of arbitrary thickness very similar in structure to mammalian corneal tissue.