CANCER VACCINE COMPOSITION

摘要

PROBLEM TO BE SOLVED: To provide a cancer treatment and/or prevention agent based on a protein as a gene product of the tumor suppressor gene WT1 (WT1 protein) or a partial peptide thereof (WT1 peptide) for a patient with malignant tumors including leukemia.SOLUTION: There are provided: a cancer vaccine composition for human leukocyte antigen (HLA)-A*0206 positive persons containing a protein as a gene product of a tumor suppressor gene WT1 or a partial peptide thereof; a cancer vaccine composition for HLA-A*0206 positive persons containing DNA or DNA encoding the WT1 protein or the WT1 peptide; a method for inducing WT1-specific CTLs; a method for inducing dendritic cells presenting a cancer antigen; a method of cancer diagnosis for HLA-A*0206 positive persons; and a method of cancer treatment or prevention.