发明名称 |
MECHANICALLY INDUCED TRAPPING OF MOLECULAR INTERACTIONS |
摘要 |
The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes. |
申请公布号 |
EP1987358(A4) |
申请公布日期 |
2013.12.04 |
申请号 |
EP20070763029 |
申请日期 |
2007.01.26 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
MAERKL, SEBASTIAN, J.;QUAKE, STEPHEN, R. |
分类号 |
G01N33/53;B01J19/00;B01L3/00;C12Q1/68;G01N33/543 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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