发明名称 MALATE SALT OF N-(4-{ [6,7-BIS(METHYLOXY)QUINOLIN-4-YL]OXY} PHENYL)-N'-(4-FLUOROPHENYL)CYCLOPROPANE-1,1-DICARBOXAMIDE, AND CRYSTALLINE FORMS THEREOF FOR THE TREATMENT OF CANCER
摘要 594594 Disclosed is N-(4-{ [6,7-bis(methoxy)quinolin-4-yl]oxy} phenyl)-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, malate salt. Also disclosed is a pharmaceutical composition comprising the N-(4-{ [6,7-bis(methyloxy)quinolin-4-yl]oxy} phenyl)-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, malate salt as defined above; and a pharmaceutically acceptable excipient, for the treatment of cancer, thyroid cancer or glioblastoma in a subject.
申请公布号 NZ594594(A) 申请公布日期 2013.11.29
申请号 NZ20100594594 申请日期 2010.01.15
申请人 EXELIXIS, INC. 发明人 GALLAGHER, WILLIAM, P
分类号 A61K31/47;A61P35/00;C07C59/245;C07D215/20;C07D215/22 主分类号 A61K31/47
代理机构 代理人
主权项
地址