POLYMORPHISM DETECTION PROBE, POLYMORPHISM DETECTION METHOD, EFFICACY DETERMINATION METHOD, AND KIT FOR DETECTING POLYMORPHISM

摘要

PROBLEM TO BE SOLVED: To provide a polymorphism detection probe which allows a V600 polymorphism in the BRAF gene to be easily detected with high sensitivity.SOLUTION: There is provided a probe for detecting a V600 polymorphism in the BRAF gene, which is (P1) a fluorescently labeled oligonucleotide which has an identity of at least 80% to a base sequence having a length of 10 to 50 bases including the 228th to the 237th bases of the base sequence indicated in a specific base sequence, wherein the base corresponding to the 237th base is cytosine labeled with a fluorescent dye, and the oligonucleotide recognizes a polymorphism in at least one of the 228th to the 230th bases of the specific base sequence.