发明名称 PERHARIDINES AS CDK INIHIBITORS
摘要 FIELD: chemistry.SUBSTANCE: invention relates to novel imidazo[4,5-b]pyridine derivatives of formula Ias well as salts, hydrates and stereoisomers thereof, where B-Rand R-A-Rare selected from groups indicated in claim 1, Rdenotes a C-Calkyl group, optionally branched, Rdenotes a hydrogen atom. The invention also relates to a compound of formula II3-substituted 7-chloro-5-iodo-imidazo[4,5b]pyridine, a method of producing imidazo[4,5-b]pyridine derivatives of formula I, a pharmaceutical composition based on the compound of formula I and use thereof.EFFECT: obtaining novel derivatives having CDK inhibiting properties.10 cl, 17 dwg, 6 tbl, 6 ex
申请公布号 RU2498984(C2) 申请公布日期 2013.11.20
申请号 RU20100108507 申请日期 2008.09.12
申请人 SENTR NAS'ONAL' DE LA RESHERSH S'ENTIFIK;JUNIVERSIT DE RENNE 1;JUNIVERSIT PARIS DESKARTE 发明人 MEZHE LORAN;BETTAJEB KARIMA;GALON EHRVE;DEMANZH LJUK;UMATA NASSIMA
分类号 C07D471/04;A61K31/437;A61P25/00;A61P29/00;A61P35/00 主分类号 C07D471/04
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