| 发明名称 |
PROTECTING MODIFIED VIRUSES FROM NEUTRALIZING ANTIBODIES USING THE REOVIRUS SIGMA 1 PROTEIN |
| 摘要 |
<p>Provided herein is a modified, non-reovirus comprising a reovirus sigma 1 protein, wherein the reovirus sigma 1 protein replaces the native attachment protein of the non-reovirus. Methods of making a modified, non-reovirus comprising a reovirus sigma 1 protein and methods of using said modified non-reovirus are also provided.</p> |
| 申请公布号 |
WO2013163724(A1) |
申请公布日期 |
2013.11.07 |
| 申请号 |
WO2013CA00250 |
申请日期 |
2013.03.15 |
| 申请人 |
ONCOLYTICS BIOTECH INC. |
发明人 |
COFFEY, MATTHEW, C.;THOMPSON, BRADLEY, G. |
| 分类号 |
C12N7/01;A61K35/76;A61P35/00;C07K14/14;C12N7/00;C12N11/16 |
主分类号 |
C12N7/01 |
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