| 发明名称 |
MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS. |
| 摘要 |
<p>The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.</p> |
| 申请公布号 |
MX2013010476(A) |
申请公布日期 |
2013.10.30 |
| 申请号 |
MX20130010476 |
申请日期 |
2012.03.13 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
SARA SABINA HADIDA-RUAH;MARK THOMAS MILLER;VIJAYALAKSMI ARUMUGAM;MICHAEL PAUL DENINNO;BRYAN A. FRIEMAN;HAYLEY MARIE BINCH;LEV TYLER DEWEY FANNING;PETER DIEDERIK JAN GROOTENHUIS;NICOLE HILGRAF;PRAMOD JOSHI;EDWARD ADAM KALLEL;JOSEPH PONTILLO;ALINA SILINA;URVI JAGDISHBHAI SHETH;DENNIS JAMES HURLEY |
| 分类号 |
C07D498/10;A61K31/424;A61P29/00 |
主分类号 |
C07D498/10 |
| 代理机构 |
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