| 发明名称 |
A METHOD FOR IDENTIFYING HETERO-MULTIMERIC MODIFIED UBIQUITIN PROTEINS WITH BINDING CAPABILITY TO LIGANDS |
| 摘要 |
<p>The present invention refers to novel hetero-multimeric proteins obtained from modified ubiquitin capable of binding the extradomain B of fibronectin (ED-B) with high affinity. Furthermore, the invention refers to fusion proteins comprising said recombinant protein fused to a pharmaceutically and/or diagnostically active component. The invention is further directed to the use of said proteins in medical treatment methods.</p> |
| 申请公布号 |
EP2379581(B1) |
申请公布日期 |
2013.10.09 |
| 申请号 |
EP20100787815 |
申请日期 |
2010.12.14 |
| 申请人 |
SCIL PROTEINS GMBH |
发明人 |
KUNERT, ANJA;NERKAMP, JOERG;STEUERNAGEL, ARND;FIEDLER, MARKUS;FIEDLER, ERIK;GOETTLER, THOMAS |
| 分类号 |
C07K14/00;C12N15/10;C40B40/02 |
主分类号 |
C07K14/00 |
| 代理机构 |
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