发明名称 BICYCLIC COMPOUNDS AS PIM INHIBITORS.
摘要 <p>The invention relates to bicyclic compounds of formula (1'), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of Pim kinase related conditions and diseases, preferably cancer.</p>
申请公布号 MX2013006467(A) 申请公布日期 2013.10.01
申请号 MX20130006467 申请日期 2011.12.07
申请人 AMGEN INC. 发明人 ANDREW TASKER;BIN WU;LIPING H. PETTUS;HUI-LING WANG;THOMAS NIXEY;VICTOR J. CEE;ROBERT M. RZASA;MATTHEW LEE;FRANK CHAVEZ JR.;KAUSTAV BISWAS;ANTHONY B. REED;SHANNON RUMFELT;CLAIRE L.M. JACKSON;BRIAN A. LANMAN;RYAN WURZ;BRADLEY HERBERICH
分类号 C07D401/14;A61K31/437;A61K31/444;A61K31/4709;A61K31/497;A61K31/506;C07D403/04;C07D403/14;C07D405/14;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D491/107;C07D498/04 主分类号 C07D401/14
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