发明名称 EQUOL-CONTAINING EXTRACT, METHOD FOR PRODUCTION THEREOF, METHOD FOR EXTRACTION OF EQUOL, AND EQUOL-CONTAINING FOOD
摘要 PROBLEM TO BE SOLVED: To provide a method for efficiently purifying an equol-containing fermented soybean hypocotyl to obtain a highly pure equol, and an extract obtained by extracting useful components containing equol, and a method for producing the same.SOLUTION: The present invention makes it possible to efficiently obtain useful components containing equol from a fermented soybean hypocotyl by subjecting an equol-containing fermented soybean hypocotyl to extraction using an ethanol aqueous solution as an extractant. The present invention reduces the content of saponin, which causes an unpleasant taste, by sequentially subjecting the equol-containing fermented soybean hypocotyl to extraction using an ethanol aqueous solution and ethanol, while efficiently extracting equol and glycitein. Purified equol is extracted from an equol-containing material by silica gel column chromatography.
申请公布号 JP2013188220(A) 申请公布日期 2013.09.26
申请号 JP20130108439 申请日期 2013.05.22
申请人 OTSUKA PHARMACEUT CO LTD 发明人 TOMINAGA MICHIAKI;TAKI TAKAO;MATSUMOTO TOSHIAKI;HANYA IZUMI;IMADA TAKUMA;MATSUOKA KUNIHIKO;KISHIMOTO TAKUYA;UCHIYAMA YUKO;TSUNEISHI HIROMASA;TSUJI MACHIKO;VALDES-GONZALEZ TANIA;TADANO KENTARO;KAMEDA KYOKO
分类号 C12P7/22;A61K31/353;A61K36/00;A61K36/48;A61P3/06;A61P5/30;A61P13/08;A61P15/00;A61P15/12;A61P19/10;A61P35/00 主分类号 C12P7/22
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