| 摘要 |
The invention provides for a brachy-therapy seed, wherein the seed includes at least two disparate radionuclides of a chemical element, the radionuclides encapsulated to form a brachytherapy seed and wherein the combination of the disparate radionuclides of the chemical element is used to augment dosimetric parameters and radiobiological characteristics of the brachytherapy seed. The invention also provides a method of manufacturing a brachytherapy seed that includes the steps of bombarding elemental silver with high energy protons produced by a cyclotron to obtain a target of 100 Pd and 103 Pd; dissolving and passing the target through a column of resin beads; placing at least one resin bead having adsorbed 100 Pd and 103 Pd into a titanium tube that is closed at one end; inserting a radiopaque member into the titanium tube; and closing the opposite end of the titanium tube.
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