发明名称 TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS
摘要 <p>The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA Aα5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.</p>
申请公布号 EP2638029(A1) 申请公布日期 2013.09.18
申请号 EP20110778911 申请日期 2011.11.07
申请人 F.HOFFMANN-LA ROCHE AG 发明人 HERNANDEZ, MARIA-CLEMENCIA;LUCAS, MATTHEW C.;THOMAS, ANDREW
分类号 C07D401/12;A61K31/4192;A61K31/4439;A61K31/497;A61P25/00;C07D403/10;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D471/04;C07D491/107 主分类号 C07D401/12
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