| 发明名称 |
METHODS FOR ONE-POT N-DEMETHYLATION/N-ACYLATION OF MORPHINE AND TROPANE ALKALOIDS |
| 摘要 |
<p>The present invention provides a method for the N-demethylation and/or N-acylation of an N-methylated heterocycle such as morphine alkaloids or tropane alkaloids. The method comprises reacting the heterocycle with an acylating agent in the presence of a metal catalyst.</p> |
| 申请公布号 |
EP2170897(B1) |
申请公布日期 |
2013.08.21 |
| 申请号 |
EP20080772837 |
申请日期 |
2008.06.30 |
| 申请人 |
BROCK UNIVERSITY |
发明人 |
CARROLL, ROBERT JAMES;LEISCH, HANNES;HUDLICKY, TOMAS;COX, D. PHILLIP |
| 分类号 |
C07D489/02;C07D451/06 |
主分类号 |
C07D489/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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