发明名称 |
Engineered cell growth on polymeric films and biotechnological applications thereof |
摘要 |
A free-standing thin film is fabricated from a structure comprising a base layer coated with a sacrificial polymer layer, which is in turn coated with a flexible polymer layer. Cells are then seeded onto the flexible polymer layer and cultured to form a tissue. The flexible polymer layer is then released from the base layer to produce a free-standing thin film comprising the tissue on the flexible polymer layer. In one embodiment, the cells are myocytes, which can be actuated to propel or displace the free-standing film. In another embodiment, the free-standing film is used to treat injured human tissue.
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申请公布号 |
US8492150(B2) |
申请公布日期 |
2013.07.23 |
申请号 |
US20070223560 |
申请日期 |
2007.02.05 |
申请人 |
PARKER KEVIN KIT;FEINBERG ADAM W.;WHITESIDES GEORGE M.;SHEVKOPLYAS SERGEY S.;FEIGEL ALEXANDER;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
PARKER KEVIN KIT;FEINBERG ADAM W.;WHITESIDES GEORGE M.;SHEVKOPLYAS SERGEY S.;FEIGEL ALEXANDER |
分类号 |
C12N5/07;C12N5/077 |
主分类号 |
C12N5/07 |
代理机构 |
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