发明名称 NEW DIHYDROINDOLONE COMPOUND, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a new composition for treatment of metastatic solid tumor and effective for inhibiting migration of cancer cells and resultant tumor progression. <P>SOLUTION: There is provided a pharmaceutical composition comprising a compound of formula (I) (in the formula, m and n are each 1 or 2; A is pyrrolyl; X is C(O), S(O) or SO<SB POS="POST">2</SB>; R<SB POS="POST">1</SB>and R<SB POS="POST">2</SB>are each alkyl or, together with nitrogen atom carrying the groups, form a heterocyclic group; R<SB POS="POST">3</SB>and R<SB POS="POST">4</SB>, together with atoms carrying the groups, form a heterocyclic group; R<SB POS="POST">5</SB>is a hydrogen atom or alkyl; and R<SB POS="POST">6</SB>is a hydrogen atom or halogen atom). <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013116908(A) 申请公布日期 2013.06.13
申请号 JP20130025505 申请日期 2013.02.13
申请人 LAB SERVIER 发明人 ORTUNO JEAN-CLAUDE;CORDI ALEXIS;FEJES IMRE;MICHAEL BURBRIDGE;HICKMAN JOHN;PIERRE ALAIN
分类号 A61K31/422;A61K31/454;A61K31/496;A61K31/5377;A61K45/00;A61P35/00;A61P35/04;A61P43/00;C07D403/14;C07D413/14;C07D417/14 主分类号 A61K31/422
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