摘要 |
<p>Compositions for stabilizing tigecycline are provided, the compositions including one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. Compositions of stabilized tigecycline are also provided comprising tigecycline and one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. The compositions can also include a cyclodextrin. Methods of preparing, uses and kits are also provided.</p> |