发明名称 COMPOSITIONS OF TIGECYCLINE AND USES THEREOF
摘要 <p>Compositions for stabilizing tigecycline are provided, the compositions including one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. Compositions of stabilized tigecycline are also provided comprising tigecycline and one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. The compositions can also include a cyclodextrin. Methods of preparing, uses and kits are also provided.</p>
申请公布号 WO2013078554(A1) 申请公布日期 2013.06.06
申请号 WO2012CA01114 申请日期 2012.12.03
申请人 UNIVERSITY HEALTH NETWORK 发明人 SCHIMMER, AARON, D.;JITKOVA, IOULIA
分类号 A61K47/22;A61K31/65;A61K47/12;A61K47/14;A61P31/04;A61P35/00;A61P35/02;C07C237/26 主分类号 A61K47/22
代理机构 代理人
主权项
地址