发明名称 |
BIOSENSOR SYSTEMS AND RELATED METHODS FOR DETECTING ANALYTES IN AQUEOUS AND BIOLOGICAL ENVIRONMENTS |
摘要 |
<p>Disclosed herein are biosensor systems and related methods for detecting analytes in aqueous and biologic environments. A biosensor system for detecting binding of an analyte of interest may include a detector configured to detect a change in an electrical property on a surface thereof. The detector may be a FET. The system also may include a passive layer disposed on a top surface of the detector. Further, the system may include a hydrophobic layer disposed on the passive layer. The system also may include a receptor-attachment material configured for binding to an analyte. A receptor may bind to the analyte, and the receptor may be attached to the receptor-attachment material. The binding of the analyte to the receptor can cause the change of the electrical property at the surface. In response to the change for example, a current may change for indicating the binding of the analyte to the receptor.</p> |
申请公布号 |
WO2013082600(A1) |
申请公布日期 |
2013.06.06 |
申请号 |
WO2012US67609 |
申请日期 |
2012.12.03 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
EVERETT, ALLEN DALE;KATZ, HOWARD;BESAR, KALPANA;HUANG, WEIGUO |
分类号 |
G01N33/50;G01N27/26;G01N33/48;G01N33/53 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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